In order to achieve the stable and precise control of industrial processes with non-linearity， hysteresis， and strong coupling， a new control method based on Local Policy Interaction Exploration-based Deep Deterministic Policy Gradient （LPIE-DDPG） was proposed for the continuous control of deep reinforcement learning. Firstly， the Deep Deterministic Policy Gradient （DDPG） algorithm was used as the control strategy to greatly reduce the phenomena of overshoot and oscillation in the control process. At the same time， the control strategy of original controller was used as the local strategy for searching， and interactive exploration was used as the rule for learning， thereby improving the learning efficiency and stability. Finally， a penicillin fermentation process simulation platform was built under the framework of Gym and the experiments were carried out. Simulation results show that， compared with DDPG， the proposed LPIE-DDPG improves the convergence efficiency by 27.3%； compared with Proportion-Integration-Differentiation （PID）， the proposed LPIE-DDPG has fewer overshoot and oscillation phenomena on temperature control effect， and has the penicillin concentration increased by 3.8% in yield. In conclusion， the proposed method can effectively improve the training efficiency and improve the stability of industrial process control.